Pharmacology Easy

Atenolol

Remember the name – A-TEN → at ten
ATENOLOL keeps the heart AT TEN, not at a hundred. The racing pulse is held to a walking pace.
It blocks beta-1 receptors on the heart and, unlike propranolol, stays largely out of the brain. Fewer nightmares and less fatigue — but also no use for tremor or stage fright.
Mnemonic: Atenolol leaves by the kidney; metoprolol by the liver
Both are beta-1 selective, so they act alike. The route of clearance is what decides which one suits a particular patient.
The mechanism comic and the patient case for Atenolol are in the app: four panels that show what the drug does in the body, and a short patient story with the practice pearl that goes with it.

Side effects

Common: fatigue, cold hands, slow heart rate

Serious: heart block, rebound if stopped suddenly

Typical dose

25–100 mg once daily

Renally cleared, so reduce the dose as eGFR falls.

Check yourself

Which beta blocker accumulates when kidney function falls?

  1. Atenolol
  2. Metoprolol
  3. Carvedilol
  4. Propranolol
Show answer

A. Atenolol

Atenolol is water-soluble and renally cleared; the other three are lipid-soluble and handled by the liver. That single property explains the bradycardia in this patient.

See it, don't memorize it

The app has the mechanism comic and a patient case for Atenolol – plus the name link, the class mnemonic, pronunciation you can hear, and a self-check, for the top 100 drugs. One purchase, no subscription, no account.

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